Exercise but not mannitol provocation increases urinary Clara cell protein (CC16) in elite swimmers

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Asthma symptoms, mannitol reactivity and exercise-induced bronchoconstriction in adolescent swimmers versus tennis players

BACKGROUND Strenuous physical activity at an elite level is associated with an increased risk for asthma and, in some sports, also prevalence of allergies. The aim of this study was to investigate the prevalence of asthma and allergy among elite swimmers and tennis players and compare airway hyperreactivity to mannitol and exercise. MATERIALS AND METHODS One hundred and one adolescent swimmer...

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Association of serum Clara cell protein CC16 with respiratory infections and immune response to respiratory pathogens in elite athletes

BACKGROUND Respiratory epithelium integrity impairment caused by intensive exercise may lead to exercise-induced bronchoconstriction. Clara cell protein (CC16) has anti-inflammatory properties and its serum level reflects changes in epithelium integrity and airway inflammation. This study aimed to investigate serum CC16 in elite athletes and to seek associations of CC16 with asthma or allergy, ...

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THE EFFECT OF AN ENDURANCE SWIMMING SESSION ON CLARA CELL PROTEIN AND CRP CONCENTRATIONS IN ELITE AND RECREATIONAL ENDURANCE MALE SWIMMERS

Background & Aims: The presence of epithelial cells in the blood is a symptom of cellular damage. Clara's cell proteins are the epithelial cells of the lungs and the respiratory tract, also, the existence of cytokines such as reactive protein C is a sign of inflammation. The purpose of the present study was to investigate the effect of one session of endurance swimming activity on the serum con...

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Daily variation in fine and ultrafine particulate air pollution and urinary concentrations of lung Clara cell protein CC16.

BACKGROUND Daily variations in ambient particulate air pollution have been associated with respiratory mortality and morbidity. AIMS To assess the associations between urinary concentration of lung Clara cell protein CC16, a marker for lung damage, and daily variation in fine and ultrafine particulate air pollution. METHODS Spot urinary samples (n = 1249) were collected biweekly for six mon...

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Clara cell specific protein (CC16) expression after acute lung inflammation induced by intratracheal lipopolysaccharide administration.

Clara cell secretory protein (CC16, CC10, or CCSP), the major secretory protein of the Clara cell, presents several biologic properties, suggesting that it may play a protective role against intrapulmonary inflammatory processes. The aim of the present study was to investigate the changes of CC16 concentrations in the lung, bronchoalveolar lavage fluid (BALF), and serum of rats with acute lung ...

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ژورنال

عنوان ژورنال: Respiratory Medicine

سال: 2011

ISSN: 0954-6111

DOI: 10.1016/j.rmed.2010.07.012